Dr Giles holds a Bachelor of Medicine, Bachelor of Surgery (Hons) and an MBA from the University of Western Australia. She is a registered medical practitioner with the Medical Board of Australia. After initially practicing as a medical doctor, Dr Giles moved to commercial pursuits which combined science, medicine and health.

Dr Giles is currently Managing Director and Chief Executive Officer of OncoRes Medical. Dr Giles is also a Venture Partner at Brandon Capital Partners, a venture capital firm dedicated to developing and supporting Australian life sciences businesses. She was previously an Investment Manager with Stone Ridge Ventures, a fund manager specialising in seed-to-early-stage technology investment.

Dr Giles has start up experience in medical apps, diagnostics and fitness devices and serves on the Boards of Sonic Healthcare, National Reconstruction Fund Corporation and the Curtin University Commercialisation Advisory Board.